!  Cognitive and affective neuroscience laboratory - Tor D. Wager, Ph. D.

 

Neuroimaging meta-analysis topics

  • Emotions

  • Working memory and executive processing

  • Attention shifting

  • Response selection and Inhibition

  • Anxiety disorders: PTSD, Social Anxiety, Specific Phobia

Cognitive Meta Summary Image

Click "Download" below to download the whole set of images and a description. Corresponding publications are posted in PDF format on the Papers section of this website.

Download

... a .zip file of Analyze format images for all meta-analyses, and a Word document containing a description of each meta-analysis.

Details:

Here you can download papers (pdf format) and images from neuroimaging meta-analyses to use as regions of interest or to compare against activation maps from individual studies. Images are provided as Analyze format images (with a .img and .hdr pair of files), and they contain numbers that reflect the density of previous reported peaks within voxels in the standard Montreal Neurologic Institute (MNI) template space (avg152t1.img). Regions not significant in the meta-analyses contain zeros. Please cite the accompanying paper if you find these maps to be useful.

 

Descriptions of meta-analyses and image files

Also found in the Word document in the Download file.

Emotion meta-analysis, 2008.  163 studies.

Wager, T. D., Barrett, L. F., Bliss-Moreau, E., Lindquist, K., Duncan, S., Kober, H., et al. (in press). The Neuroimaging of Emotion. In M. Lewis (Ed.), Handbook of Emotion.

Description

Image name (.img and .hdr pair)

Random FX

Thresh

Activations combined across emotion tasks

EMOActivation_FWE_height.img
EMOActivation_FWE_extent.img
EMOActivation_FWE_all.img

Yes

T

 

 

 

 

Experienced emotion vs. perception of emotional stimuli

Mode_Exp-Per_Pos_FWE_height.img Mode_Exp-Per_Pos_FWE_extent.img Mode_Exp-Per_Pos_FWE_all.img

Yes

T

Perception of emotional stimuli vs. Experienced emotion

Mode_Exp-Per_Neg_FWE_height.img
Mode_Exp-Per_Neg_FWE_extent.img
Mode_Exp-Per_Neg_FWE_all.img

Yes

T

Positive vs. negative emotional experience

Valence_Neg-Pos_Neg_FWE_height.img
Valence_Neg-Pos_Neg_FWE_extent.img
Valence_Neg-Pos_Neg_FWE_all.img

Yes

T

Negative vs. positive emotional experience

Valence_Neg-Pos_Pos_FWE_height.img
Valence_Neg-Pos_Pos_FWE_extent.img
Valence_Neg-Pos_Pos_FWE_all.img

Yes

T

 

 

 

 

Note.  All maps are corrected for multiple comparisons across the brain (gray matter plus boundary). ‘Height’-based correction is based on the proportion of contrast maps with activation, and is the most spatially precise. ‘Extent’-based correction is based on the size of the contiguous region at an arbitrary primary threshold.  These results are also corrected for multiple comparisons, but they are less spatially precise. ‘all’ refers to a mask that includes voxels significant with either height- or extent-based correction. Abbreviations: Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U).  Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).

 

Anxiety disorders meta-analysis, 2007.  30 studies.
Etkin, A., & Wager, T. D. (2007). Functional Neuroimaging of Anxiety: a Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder and Specific Phobia. American Journal of Psychiatry.

Description

Image name

Random FX

Thresh

Consistent activations in fear conditioning studies

Fear_conditioning_p005.img

Yes

T

 

 

 

 

Note on abbreviations.  Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U).  Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred). P < .005 refers to the uncorrected voxel-wise p-value threshold.

 

Inhibition meta-analysis, 2006.  47 studies.
Nee, D. E., Wager, T. D., & Jonides, J. (2007). Interference resolution: Insights from a meta-analysis of neuroimaging tasks. Cogn Affect Behav Neurosci, 7(1), 1-17.

Description

Image name

Random FX

Thresh

Activations combined across tasks

inhib_idens15_enl.img

No

T

Flanker task peak density

flanker15.img

No

U

Go/No go task peak density

gng15.img

No

U

Stimulus/response compatibility peak density

src15.img

No

U

Stroop peak density

stroop15.img

No

U

 

 

 

 

Note on abbreviations.  Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U).  Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).

 

Attention switching, 2004.  31 studies.
Wager, T. D., Reading, S., & Jonides, J. (2004). Neuroimaging studies of shifting attention: a meta-analysis. Neuroimage, 22(4), 1679-1693.

Description

Image name

Random FX

Thresh

Switch vs. non-switch comparison combined across switch types

switch_clusters_mix_final.img

No

T

 

 

 

 

Note on abbreviations.  Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U).  Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).

 

Emotions meta-analysis, 2003.  64 studies
Wager, T. D., Phan, K. L., Liberzon, I., & Taylor, S. F. (2003) Valence, gender, and lateralization of functional brain anatomy in emotion: A meta-analysis of findings from neuroimaging. Neuroimage, 19, 513-531.
           


Description

Image name (.img and .hdr pair)

Random FX

Thresh

Approach vs. avoidance emotions

ap-av_enl.img

No

T

Avoidance vs. approach emotions

av-ap_enl.img

No

T

Approach-related emotions

dens_ap.img

No

U

Avoidance-related emotions

dens_av.img

No

U

Note on abbreviations.  Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U).  Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).

 

Working memory meta-analysis, 2003.  60 studies
Wager, T. D. & Smith, E. E. (2003). Neuroimaging and working memory: A meta-analysis. Cognitive, Affective, and Behavioral Neuroscience, 3, 255-274.

Description

Image name

Random FX

Thresh

Working memory storage

dens_exec-noexec_thr.img

No

T

Working memory storage

dens_noexec.img

No

U

Executive WM vs. simple storage

dens_exec-noexec_thr.img

No

T

Executive WM vs. simple storage

dens_exec-noexec.img

No

U

Note on abbreviations.  Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U).  Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).

 

 

 

Flowcharts and diagrams

Click on an image below to download it:

 

 

 

 

 

 

 

 !   Images to download

Download the .img and .hdr files for the meta-analyses by clicking on "Download" at left. Each meta-analysis is associated with a paper, and the citation is listed with the paper.

All papers are linked to PDF files on the Papers section of the website. Click on the citation to download a pdf version of the paper.

The images can be used to mask results from individual studies and/or determine independent regions of interest (ROIs) for use in individual studies.

Internal files for collaborators (restricted access)


©2003 Tor Wager no-link no-link SoftwareMeta-analysisLabPapersArt