Neuroimaging meta-analysis topics
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Emotions
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Working memory and executive processing
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Attention shifting
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Response selection and Inhibition
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Anxiety disorders: PTSD, Social Anxiety, Specific Phobia
Click "Download" below to download the whole set of images and a description. Corresponding publications are posted in PDF format on the Papers section of this website.
Download
... a .zip file of Analyze format images for all meta-analyses, and a Word document containing a description of each meta-analysis.
Details:
Here you can download papers (pdf format) and images from neuroimaging meta-analyses to use as regions of interest or to compare against activation maps from individual studies. Images are provided as Analyze format images (with a .img and .hdr pair of files), and they contain numbers that reflect the density of previous reported peaks within voxels in the standard Montreal Neurologic Institute (MNI) template space (avg152t1.img). Regions not significant in the meta-analyses contain zeros. Please cite the accompanying paper if you find these maps to be useful.
Descriptions of meta-analyses and image files
Also found in the Word document in the Download file.
Emotion meta-analysis, 2008. 163 studies.
Wager, T. D., Barrett, L. F., Bliss-Moreau, E., Lindquist, K., Duncan, S., Kober, H., et al. (in press). The Neuroimaging of Emotion. In M. Lewis (Ed.), Handbook of Emotion.
Description |
Image name (.img and .hdr pair) |
Random FX |
Thresh |
Activations combined across emotion tasks |
EMOActivation_FWE_height.img |
Yes |
T |
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Experienced emotion vs. perception of emotional stimuli |
Mode_Exp-Per_Pos_FWE_height.img Mode_Exp-Per_Pos_FWE_extent.img Mode_Exp-Per_Pos_FWE_all.img |
Yes |
T |
Perception of emotional stimuli vs. Experienced emotion |
Mode_Exp-Per_Neg_FWE_height.img |
Yes |
T |
Positive vs. negative emotional experience |
Valence_Neg-Pos_Neg_FWE_height.img |
Yes |
T |
Negative vs. positive emotional experience |
Valence_Neg-Pos_Pos_FWE_height.img |
Yes |
T |
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Note. All maps are corrected for multiple comparisons across the brain (gray matter plus boundary). ‘Height’-based correction is based on the proportion of contrast maps with activation, and is the most spatially precise. ‘Extent’-based correction is based on the size of the contiguous region at an arbitrary primary threshold. These results are also corrected for multiple comparisons, but they are less spatially precise. ‘all’ refers to a mask that includes voxels significant with either height- or extent-based correction. Abbreviations: Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U). Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).
Anxiety disorders meta-analysis, 2007. 30 studies.
Etkin, A., & Wager, T. D. (2007). Functional Neuroimaging of Anxiety: a Meta-Analysis of Emotional Processing in PTSD, Social Anxiety Disorder and Specific Phobia. American Journal of Psychiatry.
Description |
Image name |
Random FX |
Thresh |
Consistent activations in fear conditioning studies |
Fear_conditioning_p005.img |
Yes |
T |
|
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Note on abbreviations. Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U). Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred). P < .005 refers to the uncorrected voxel-wise p-value threshold.
Inhibition meta-analysis, 2006. 47 studies.
Nee, D. E., Wager, T. D., & Jonides, J. (2007). Interference resolution: Insights from a meta-analysis of neuroimaging tasks. Cogn Affect Behav Neurosci, 7(1), 1-17.
Description |
Image name |
Random FX |
Thresh |
Activations combined across tasks |
inhib_idens15_enl.img |
No |
T |
Flanker task peak density |
flanker15.img |
No |
U |
Go/No go task peak density |
gng15.img |
No |
U |
Stimulus/response compatibility peak density |
src15.img |
No |
U |
Stroop peak density |
stroop15.img |
No |
U |
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|
Note on abbreviations. Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U). Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).
Attention switching, 2004. 31 studies.
Wager, T. D., Reading, S., & Jonides, J. (2004). Neuroimaging studies of shifting attention: a meta-analysis. Neuroimage, 22(4), 1679-1693.
Description |
Image name |
Random FX |
Thresh |
Switch vs. non-switch comparison combined across switch types |
switch_clusters_mix_final.img |
No |
T |
|
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|
Note on abbreviations. Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U). Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).
Emotions meta-analysis, 2003. 64 studies
Wager, T. D., Phan, K. L., Liberzon, I., & Taylor, S. F. (2003) Valence, gender, and lateralization of functional brain anatomy in emotion: A meta-analysis of findings from neuroimaging. Neuroimage, 19, 513-531.
Description |
Image name (.img and .hdr pair) |
Random FX |
Thresh |
Approach vs. avoidance emotions |
ap-av_enl.img |
No |
T |
Avoidance vs. approach emotions |
av-ap_enl.img |
No |
T |
Approach-related emotions |
dens_ap.img |
No |
U |
Avoidance-related emotions |
dens_av.img |
No |
U |
Note on abbreviations. Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U). Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).
Working memory meta-analysis, 2003. 60 studies
Wager, T. D. & Smith, E. E. (2003). Neuroimaging and working memory: A meta-analysis. Cognitive, Affective, and Behavioral Neuroscience, 3, 255-274.
Description |
Image name |
Random FX |
Thresh |
Working memory storage |
dens_exec-noexec_thr.img |
No |
T |
Working memory storage |
dens_noexec.img |
No |
U |
Executive WM vs. simple storage |
dens_exec-noexec_thr.img |
No |
T |
Executive WM vs. simple storage |
dens_exec-noexec.img |
No |
U |
Note on abbreviations. Thresh: Thresholded mask (T) containing significant regions, or unthresholded peak density (U). Random FX: contrast map is random effect (Yes, preferred) or fixed (not preferred).
Flowcharts and diagrams
Click on an image below to download it:
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Download the .img and .hdr files for the meta-analyses by clicking on "Download" at left. Each meta-analysis is associated with a paper, and the citation is listed with the paper. All papers are linked to PDF files on the Papers section of the website. Click on the citation to download a pdf version of the paper. The images can be used to mask results from individual studies and/or determine independent regions of interest (ROIs) for use in individual studies. |