Note:
Click on the appropriate link to download/view a copy of the reading. Not all readings are required, so check the syllabus!
BasicGenetics:
- DNA and the Genetic Code:
- What is a gene? (General)
- Genetic Regulation and Epigenesis:
- Sex Development: Wilhelm & Koopman (2006)
- Primate Gene Expression: Khaitovich et al. (2006)
- Hox Genes: Pearson et al. (2005)
- DNA Methylation: Robertson (2005)
- Epigenomics: Fazzari & Greally (2004)
- Epistasis: Hughes (2005)
- Microarray Technology: Hoheisel (2006)
- Mendelian Traits:
- Hemophilia: Graw et al. (2005)
- X-linked Mental Retardation: Ropers & Hamel (2005)
- Phenylketonuria: NIH Consensus Panel (2000)
- Phenylketonuria: Scriver (2007)
- Congenital Adrenal Hyperplasia & Prenatal Hormones: Cohen-Bendahan et al. (2005)
- Gene-environment Interaction in Human Diseases: Hunter (2005)
- Disorders with Complex Gennetics:
- Introduction & Terminology: Hemminki, Bermejo & Forsti (2006)
- Alzheimers: Bertram et al. (2005)
- Addictions (Molecular Genetics): Goldman et al. (2005)
- Human Obesity: Bell et al. (2005)
- Prions: Shorter & Lindquist (2005)
- Common Disease Rare Variant: Pritchard (2001)
- Chromosomes:
- Down Syndrome: Antonarakis et al. (2004)
- Polymorphisms:
- HapMap Project (General)
- Structural Variants: Feuk et al. (2006a)
- Structural Variants: Feuk et al. (2006b)
- Gene Expression: Cheung et al. (2005)
- Automated DNA Sequencer
- Detecting CNVs: Carter (2007)
- 1000 Genomes (2010a)
- 1000 Genomes (2010b)
- Linkage and Association Designs:
- Population-based Statistical Methods: Balding (2006)
- Family-based Statistical Methods: Laird & Lange (2006)
- Confounding Factors: Zondervan & Cardon (2004)
- Haplotypes: Cardon & Abecasis (2003)
- Population Stratification: Freedman et al., (2004)
- Genome-wide Association: Hirschhorn & Daly (2005)
- Genome-wide Association: Wang et al. (2005)
- Gene-centric Approach: Jorgenson & Witte (2006)
- GWAS: Simple Introduction: Pearson & Manolio (2008)
- GWAS: Overview of current studies: Donnelly (2008)
- Quantitative Methodology:
- Assotiation (Population-based): Balding (2006)
- Association(Family-based): Laird & Lange (2006)
- Bayesian Estimation & MCMC: Beaumont & Rannala (2004)
- Confidence Intervals: Neale & Miller (1997)
- G x E Interaction: Eaves (2006)
- G x E Interaction: Purcell (2004)
- GWAS (Height): Vissher (2008)
- GWAS & heritability: Gibson (2010)
- Haplotypes: Cardon & Abecasis (2003)
- Heritability: Vissher et al. (2008)
- MALD: Smith & O'Brien (2005)
- Markov Chain Monte Carlo: Eaves & Erkanli (2003)
- Multifactorial Transmission: Bodmer & Bonilla (2008)
- HANDOUT: Twin concordance and ascertainment (mathematical)
- HANDOUT: Partitioning Genetic Variance
- HANDOUT: Partitioning Genetic Variance (similar but more general than the above handout)
- HANDOUT: How to analyze a population-based association design
- Intelligence & its Role in Modern Society:
- Mental Retardation: Flint (1999)
- X-linked Mental Retardation: Ropers & Hamel (2005)
- IQ (APA Committee on The Bell Curve): Neisser et al. (1996)
- Spearman's g: Lubinski (2004)
- The Flynn Effect: Flynn (1999)
- Mental Retardation:
- General:
- Personality
- Structure of Personality: Loehlin et al. (1998)
- Structure of Personality: McCrae et al. (2001)
- Structure of Personality: Yamagata et al. (2006)
- Structure: Big 5: Jang et al. (2006)
- Methods: Carey & DiLalla (1994)
- Structure: Markon, Kreuger & Watson (2005)
- Externalizing behavior: Kreuger et al. (2002)
- Childhood & Adolescence: Fruyt et al. (2006)
- Adults: McGue, Bacon & Lykken (1993)
- Adults: Hershberger, Plomin & Pedersen (1995)
- Elderly: Johnson, McGue & Krueger (2005)
- DRD4 interaction with friends: Settle et al. (2010)
- Critique of Methods: Kendler (2005)
- Meaning: Kendler (2005)
- Overall Perspective: Fanous & Kendler (2005)
- Overall Perspective: Burmeister et al. (2008)
- Endophenotypes (Meaning & Origin): Gottesman & Gould (2003)
- Example of Endophenotypes: Dick et al. (2006)
- ADHD & CNVs: Williams et al. (2010)
- Autism: Autism Consortium (2007)
- Autism & CNVs: Sebat et al. (2007)
- Autism Spectrum, Schizophrenia & CNVs: Merikangas et al. (2009)
- Schizophrenia: Non-technical summary of genetics: Wray & Visscher (2010)
- Schizophrenia: Intl. Schizophrenia Consortium GWAS: Purcell et al. (2009)
- Human Origins: Garrigan & Hammer (2006)
- X Chromosome Evolution: Vicoso & Charlesworth (2006)
- Mate Choice: Chenoweth & Blows (2006)
- Social Behavior(Molecular Genetics): Robinson et al. (2005)
- Adaptation & Evolution: Orr (2005)
- Evolution of Language: Fisher & Marcus(2005)
- Gene-culture coevolution (lactase): Beja-Pereira et al. (2005)
- Human Brain Evolution: Preuss et al. (2004)
- Human Brain Evolution (DUF1220): Popesco et al. (2006)
- Human Brain Size (ASPM): Mekel-Bobrov et al. (2005)
- Human Brain Size (Microcephalin): Evans et al. (2005)
- Human Brain Size (ASPM & Microcephalin): Mekel-Bobrov et al. (in press)
- Rat Genetics: Smits & Cuppen (2006)
- Alcohol & Alcoholism: Demarest et al. (2005)
- Rodent QTLs: Flint et al. (2005)
- Genome-wide Screens: Carpenter & Sabatini (2004)
- Drosophila Quantantitative Analysis: Anholt & Mackay (2004)
- Mouse Models of Psychosis: Arguello & Gogos (2006)
- QTLs & Mouse Anxiety: Henderson et al. (2004)
- Sociality & Vasopressin: Young et al. (1999) (2004)
- Laboratory Effects: Crabbe, Wahlsten & Dudek (1999)
- Structure of Personality
- ... and Psychopathology
- Development, Continuity & Change
- Social Attitudes and Politics
- Psychopathology:
- General
- Endophenotypes:
- Disorders:
- Evolution:
- Animal Models:
Controversies and Other Topics:
- Should we limit molecular genetic studies of behavior?
- YES! Merikangas & Risch (2003)
- NO! Berretinni et al. (2003)(
Class Motto:
Quantum materiae materietur marmota monax si marmota monax materiam possit materiari?